COTA (USA)

Database Contact Data

Email 1: info@cotahealthcare.com
Email 2: COTA Life Sciences <lifesciences@cotahealthcare.com>

Alternate Contact

If you cannot reach the database manager, please try completing the contact form at:
https://cotahealthcare.com/contact/

References of Studies Using/Describing Database

1. Crombie JL, Jun M, Wang T, Mutebi A, Wang A, Chhibber A, Kamalakar R, Ukropec J, Blaedel J, Kalsekar A. Real-world outcomes with novel therapies in relapsed/refractory diffuse large B-cell lymphoma. Leuk Lymphoma. 2024 Nov;65(11):1623-1633.

2. Spira A, Waters D, Ran T, Vadagam P, He J, Vanderpoel J, Donnelly A, Lin I. PP01. 68 Real-World Treatment Patterns of Patients with EGFR Exon 20 Insertion-Mutated Advanced NSCLC Treated with Amivantamab or Mobocertinib after Platinum-Based Chemotherapy. Journal of Thoracic Oncology. 2024 Jul 1;19(7):e32.

3. Sinyavskaya L, Meche A, Faucher A, Hlavacek P, Johnson SMA, DiBonaventura M, Vekeman F, Ren J, Schepart A. Assessment of algorithms for identifying patients with triple-class refractory multiple myeloma using real-world data. Curr Med Res Opin. 2024 May;40(5):789-801.

4. Sineshaw HM, Zettler CM, Prescott J, Garg M, Chakraborty S, Sarpong EM, Bai C, Belli AJ, Fernandes LL, Wang CK. Real‐world patient characteristics, treatment patterns, and treatment outcomes of patients with diffuse large B‐cell lymphoma by line of therapy. Cancer Medicine. 2024 Apr;13(7):e7173.

5. Ip A, Mutebi A, Wang T, Jun M, Kalsekar A, Navarro FR, Wang A, Kamalakar R, Sacchi M, Elliott B. Treatment Outcomes with Standard of Care in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Real-World Data Analysis. Adv Ther. 2024 Mar;41(3):1226-1244.

6. Naomi Dempsey et al., A retrospective, descriptive analysis of a single-center experience with patients with metaplastic breast cancer. Journal of Clinical Oncology. 2024;42:16_suppl: e13173-e13173.

7. Shaji Kumar et al., Comparative effectiveness of linvoseltamab versus standard-of-care (SOC) treatment (tx) in real-world patients (pts) in the United States (US) with triple-class exposed (TCE) relapsed/refractory multiple myeloma (RRMM). Journal of Clinical Oncology. 2024;42:16_suppl: 7561-7561.

8. Costa LJ, LeBlanc TW, Tesch H, Sonneveld P, Kyle RP, Sinyavskaya L, Hlavacek P, Meche A, Ren J, Schepart A, Aydin D, Nador G, DiBonaventura MD. Elranatamab efficacy in MagnetisMM-3 compared with real-world control arms in triple-class refractory multiple myeloma. Future Oncol. 2024;20(17):1175-1189.

9. Dhanda R, Wang CK, Belli AJ. Best Practices in the Curation and Use of Real-world Data in the Regulatory Pathway. Medicon Medical Sciences. 2023 Nov; 5(5): 38-40.

10. Hoff FW, Patel PA, Belli AJ, Hansen E, Foss H, Schulte M, Wang CK, Madanat YF. Real-world outcomes of frontline venetoclax-based therapy in older adults with acute myeloid leukemia: an analysis utilizing EHR data. Leuk Lymphoma. 2023 Apr 13:1-6.

9/4/20: 95th profile from USA: Flatiron RWE Data for Oncology

The Flatiron Health database is a longitudinal and nationwide database comprised of de-identified patient-level structured and unstructured data from an EHR data source, curated via technology-enabled abstraction. It includes de-identified data from >280 cancer clinics representing more than 2.5 million U.S. cancer patients.

Keep a look out for our latest poster, Data Sources for Studying Genetic Factors of Chronic Obstructive Pulmonary Disease (COPD), to be presented at ICPE 2020 (Sep. 16-17, 2020).

Flatiron RWE Data for Oncology (USA)

Database Contact Data

Flatiron Heath 
233 Spring Street
New York, NY 10013
USA
(Submit requests online at https://flatiron.com/contact/)

Alternate Contact

N/A

References of Studies Using/Describing Database

1. Rugo HS, Liu X, Li B, McRoy L, Chen C, Layman RM, Brufsky A. Real-world treatment patterns for palbociclib plus an aromatase inhibitor, or an aromatase inhibitor alone, for patients with metastatic breast cancer in the Flatiron Database. Int J Cancer. 2024 Feb 15;154(4):701-711.

2. Nicholson G, Carlson KB, Hernandez RK, Schenfeld J, Cadieux B, Henry D, De Sousa Barbosa VJ, Saad H. Treatment Patterns of Bone-targeting Agents Among Solid Tumor Patients With Bone Metastases: An Analysis of Electronic Health Record Data in the United States From 2014 to 2018. Am J Clin Oncol. 2024 Jan 11. doi: 10.1097/COC.0000000000001075. Epub ahead of print.

3. Castellanos EH, Wittmershaus BK, Chandwani S. Raising the Bar for Real-World Data in Oncology: Approaches to Quality Across Multiple Dimensions. JCO Clin Cancer Inform. 2024 Jan;8:e2300046.

4. Hantel A, Cernik C, Uno H, Walsh TP, Calip GS, DeAngelo DJ, Lathan CS, Abel GA. Sociodemographic associations with uptake of novel therapies for acute myeloid leukemia. Blood Cancer J. 2023 Dec 21;13(1):192.

5. Passamonti F, Lou Y, Chevli M, Abraham P. Real-world outcomes with fedratinib therapy in patients who discontinued ruxolitinib for primary myelofibrosis. Future Oncol. 2023 Nov 22. doi: 10.2217/fon-2022-1256.

6. Brufsky A, Liu X, Li B, McRoy L, Chen C, Layman RM, Rugo HS. Palbociclib Combined with an Aromatase Inhibitor in Patients with Breast Cancer with Lung or Liver Metastases in US Clinical Practice. Cancers (Basel). 2023 Nov 2;15(21):5268.

7. Rugo HS, Liu X, Li B, McRoy L, Chen C, Layman RM, Brufsky A. Real-World Effectiveness of Palbociclib Plus Aromatase Inhibitors in African American Patients With Metastatic Breast Cancer. Oncologist. 2023 Oct 3;28(10):866-874.  

8. Eyre TA, Hess LM, Sugihara T, He D, Khanal M, Pagel JM, Walgren RA, B Abada P, Konig H, Roeker LE, Mato A. Clinical outcomes among patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) who received treatment with a covalent BTK and BCL2 inhibitor in the United States: a real-world database study. Leuk Lymphoma. 2023 May;64(5):1005-1016.

9. Zeidan AM, Pollyea DA, Borate U, Vasconcelos A, Potluri R, Rotter D, Kiendrebeogo Z, Gaugler L, Prebet T, Strocchia M, Bonifacio G, Chen C. Venetoclax plus azacitidine compared with intensive chemotherapy as induction for patients with acute myeloid leukemia: retrospective analysis of an electronic medical record database in the United States. Ann Hematol. 2023 Apr;102(4):749-754.

10. Rugo HS, Raskina K, Schrock AB, Madison RW, Graf RP, Sokol ES, Sivakumar S, Lee JK, Fisher V, Oxnard GR, Tukachinsky H. Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma. Clin Cancer Res. 2023 Mar 14;29(6):1056-1067.

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