AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) (USA)
Database Contact Data
Shawn M. Sweeney, PhD
Director, AACR Project GENIE Coordinating Center
Executive Office
American Association for Cancer Research
615 Chestnut Street, 17th Floor
Philadelphia, PA 19106-4404
USA
Phone: +1 215-446-7148 (Direct)
Fax: +1 267-765-1043
Email: shawn.sweeney@aacr.org
Alternate Contact
AMERICAN ASSOCIATION FOR CANCER RESEARCH
615 Chestnut St., 17th Floor
Philadelphia, PA 19106-4404
USA
Phone: +1 215-440-9300
Email: aacr@aacr.org
References of Studies Using/Describing Database
1. Bobbili PJ, Ivanova J, Solit DB, Mettu NB, McCall SJ, Dhawan M, DerSarkissian M, Arondekar B, Chang J, Niyazov A, Lee J. Treatment patterns and clinical outcomes among patients with metastatic prostate cancer harboring homologous recombination repair mutations. Clinical Genitourinary Cancer. 2024 Jun 1;22(3):102080.
2. Kehl KL, Lavery JA, Brown S, Fuchs H, Riely G, Schrag D, Newcomb A, Nichols C, Micheel CM, Bedard PL, Sweeney SM. Biomarker Inference and the Timing of Next-Generation Sequencing in a Multi-Institutional, Cross-Cancer Clinicogenomic Data Set. JCO Precision Oncology. 2024 Mar;8:e2300489.
3. Sanz-Garcia E, Brown S, Lavery JA, Weiss J, Fuchs HE, Newcomb A, Postle A, Warner JL, LeNoue-Newton ML, Sweeney SM, Pillai S. Genomic characterization and clinical outcomes of patients with peritoneal metastases from the AACR GENIE Biopharma Collaborative colorectal cancer registry. Cancer Research Communications. 2024 Feb 20;4(2):475-86.
4. de Bruijn I, Kundra R, Mastrogiacomo B, Tran TN, Sikina L, Mazor T, Li X, Ochoa A, Zhao G, Lai B, Abeshouse A. Analysis and visualization of longitudinal genomic and clinical data from the AACR project GENIE biopharma collaborative in cBioPortal. Cancer research. 2023 Dec 1;83(23):3861-7.
5. Choudhury NJ, Lavery JA, Brown S, de Bruijn I, Jee J, Tran TN, Rizvi H, Arbour KC, Whiting K, Shen R, Hellmann M. The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non–Small Cell Lung Cancer. Clinical Cancer Research. 2023 Sep 1;29(17):3418-28.
6. Choudhury NJ, Lavery JA, Brown S, de Bruijn I, Jee J, Tran TN, Rizvi H, Arbour KC, Whiting K, Shen R, Hellmann M. The GENIE BPC NSCLC cohort: a real-world repository integrating standardized clinical and genomic data for 1,846 patients with non-small cell lung cancer. Clinical Cancer Research. 2023 May 24:CCR-23.
7. Lavery JA, Brown S, Curry MA, Martin A, Sjoberg DD, Whiting K. A data processing pipeline for the AACR project GENIE biopharma collaborative data with the {genieBPC} R package. Bioinformatics. 2023 Jan;39(1):btac796.
8. Scharpf RB, Balan A, Ricciuti B, Fiksel J, Cherry C, Wang C, Lenoue-Newton ML, Rizvi HA, White JR, Baras AS, Anaya J. Genomic Landscapes and Hallmarks of Mutant RAS in Human Cancers. Cancer research. 2022 Nov 2;82(21):4058-78.
9. LeNoue-Newton ML, Chen SC, Stricker T, Hyman DM, Blauvelt N, Bedard PL, Meric-Bernstam F, Punglia RS, Schrag D, Lepisto EM, Andre F. Natural history and characteristics of ERBB2-mutated hormone receptor–positive metastatic breast cancer: a multi-institutional retrospective case–control study from AACR project GENIE. Clinical Cancer Research. 2022 May 13;28(10):2118-30.
10. Brown S, Lavery JA, Shen R, Martin AS, Kehl KL, Sweeney SM, Lepisto EM, Rizvi H, McCarthy CG, Schultz N, Warner JL, Park BH, Bedard PL, Riely GJ, Schrag D, Panageas KS; AACR Project GENIE Consortium. Implications of Selection Bias Due to Delayed Study Entry in Clinical Genomic Studies. JAMA Oncol. 2022 Feb 1;8(2):287-291.
Vinay Mehta, PhD, MS
B.R.I.D.G.E TO DATA (BTD) is the prevailing resource for capturing detailed global metadata on real-world databases. The developers of BTD have spent meticulous thought into creating a process for collecting (and maintaining) data by building relationships with key data vendors across the world. With the breadth and magnitude of global real-world data available, it’s a testament to the scientific staff at BTD to successfully achieve such an ambitious undertaking.